I have been scanning slides at the highest resolution with the noise reduction on but no color management or adjustments made during scanning (preferring to work on the scanned image in Photoshop). Overall scan quality is excellent with no issues from a functional or performance perspective from any of the approx. 1000 scans done to date. The noise reduction capabilities are the primary benefit I notice in that the time spent touching up dust and minor scratches afterwards is very very minor (and usually due to forgetting to clean the slides in the first place!). Color balance and detail resolution are far superior to what I experienced beforehand. Desk footprint is great and noise level while scanning is comfortable.

If I had any complaint at all it is that the scans can reveal problems in the original image such as a lack of sharpness in some areas of the image due to me using lower quality lenses in the old days - such problems don't show up quite so easily either when viewing the slides through a loupe or after the 2400dpi scans - serves me right for using cheap glass, I guess.